Born to a family with a sports background with Maria Stella as a disc throwing athlete and his father Adriano Buffon as a weightlifting athlete, Buffon was the first child of three siblings. His two younger sisters, Veronica and Guendalina, are currently working as volleyball athletes. Uncle Buffon himself, Angelo Masocco, also works as a basketball athlete. One of Italy's legendary goalkeepers, Lorenzo Buffon, also has blood ties with Gianluigi Buffon's grandfather.
Buffon is currently engaged to the Czech model Alena Šeredová. The couple has two children, Louis Thomas (born 28 December 2007) and David Lee (born 31 October 2009). Buffon's first child was named "Thomas" on the basis of Thomas Nkono, who was idol Buffon's goalkeeper. Buffon is good friends with several footballers including Alessandro Del Piero and Pavel Nedved.
Gianluigi Buffon made his debut for the Italian national football team on October 29, 1997 at the age of 19 as a substitute for injured Gianluca Pagliuca while facing the 1998 World Cup play-off against the Russian national football team. He later entered into 23 players who played in the 1998 World Cup but he did not get the chance to play though. Buffon also included members of the Italian team at the 1996 Atlanta Olympics, 2002 World Cup and Euro 2004. Buffon was actually Dino Zoff's first choice in the 2000 European Cup but only eight days before the tournament his hand broke and he was replaced by Francesco Toldo.
During the 2006 World Cup finals in Germany, Buffon appeared on an extraordinary form because he only conceded two goals and recorded five clean sheets. Buffon's other record in PD 2006 was that he didn't concede for 453 minutes. Two goals nested in Buffon's goal were the moment of Cristian Zaccardo's own goal against the United States national football team and a penalty in the final from Zinedine Zidane (French soccer national team) Buffon also became a hero in the 2006 PD final match precisely when the penalty shootout took place after France held Italy to a 1-1 draw. Buffon managed to hold the kick David Trezeguet and with a penalty from Fabio Grosso, Italy finally managed to become a world champion of 2006. From these accomplishments, Buffon then got grace Lev Yashin Award for outstanding performing during 2005-2006.
At Euro 2008, Gianluigi Buffon got the chance to appear as captain of the national team after Fabio Cannavaro withdrew from the tournament due to injury. In the group stage match against the Romanian national football team on June 13, Buffon managed to save a penalty from Adrian Mutu and the match ended in a 1-1 score. Buffon then performed superbly against France in the final group match, but unfortunately Buffon's extraordinary performance had to end when he played against the Spanish national football team in the quarter-finals 9 days later, because Italy was forced to give up 4-2 on penalties, and Buffon was only can fend off a penalty kick from Spain.