On March 8, 1971 in New York, Frazier won a number over Muhammad Ali while defending his title in a battle dubbed the Fight of the Century. However, Ali avenged his defeat from Frazier on January 28, 1974 with the victory of numbers. In the deciding match in Manila, October 1, 1975, Ali again defeated Frazier. At that time, Frazier's coach, Eddie Futch, threw a towel into the 15th round because Frazier lost his eyesight for a while. The brutal match was remembered as Thrilla in Manila.
Frazier lost his title after losing TKO in the second round to George Foreman, in a match in Kingston, Jamaica, January 22, 1973. Frazier again faced Foreman on 15 July 1976, but Frazier lost again with the TKO in the fifth round. Frazier hung boxing gloves in 1981. In total, Frazier's record is 32 wins, one draw and four defeats. The four defeats were when facing Muhammad Ali and Foreman, each losing twice.