1. Doctor Octopus
Dr. Otto Octavius, better known as Doctor Octopus, is a fictional Marvel Comics supervillain, and a regular enemy of Spider-Man. He was created by Stan Lee and Steve Ditko, and first appeared in Amazing Spider-Man #3 (July 1963). Doctor Octopus is often thought of as a low-level telepathic mutant, as he can mentally control the mechanical arms on his armor. But so far he has never shown any sign of superpowers. Well Dr. Octopus a genius of atomic physics and robotics. Dr. Octopus always wears a special armor with four mechanical, mentally controlled tentacles. These extra arms can lift objects up to eight tons, if at least one arm is used to lift Dr. Octopus' body. Through his arms, Dr. Octopus also climbs walls with ease and travels over any terrain at lightning speed. The arms also serve as weapons. Dr. Octopus' concentration and control over the arms has improved so much over time that he can even fight several enemies at the same time with the arms while he is busy with something else.
Bane is a fictional supervillain from DC Batman comics. He was created by Chuck Dixon, Doug Moench and Graham Nolan and made his debut in January 1993 in the one-shot Batman: Vengeance of Bane. Bane is naturally as strong as a man his age and height can be. The drug Venom allows him to increase his strength even further to superhuman level. Bane is also highly intelligent, a good fighter, strategist and buoy king. He also masters at least six languages.
3. Doctor Doom
Doctor Doom, real name Victor von Doom, is a fictional Marvel Comics supervillain. Doctor Doom was created by Stan Lee and Jack Kirby and first appeared in the fifth issue (July 1962) of The Fantastic Four. Doom's origins were fully told in Fantastic Four Annual #2 (1964). Doom is one of the greatest geniuses in the world. He was once Reed Richards' classmate. Since Richards was his equal in intelligence, Doom developed an enormous hatred and jealousy towards him. Doom is seen as the nemesis of the Fantastic Four, but has also battled other superheroes such as The Vergelders, Silver Surfer, Hulk, Captain America, Daredevil, Iron Man, and Spider-Man. He also sometimes gets into trouble with fellow super villains such as Venom. From time to time, however, he has also helped the superheroes on a number of occasions in battles against enemies who also posed a threat to him.
4. Green Goblin
The Green Goblin is a fictional Marvel Comics supervillain, and one of Spider-Man's greatest enemies. Created by Stan Lee and Steve Ditko. He first appeared in Amazing Spider-Man #14 (July 1964). The Green Goblin is most notorious as a supervillain for his murder of Spider-Man's girlfriend Gwen Stacy. That also earned him the title of Spider-Man's most dangerous opponent. The serum that turned Norman Osborn, and later his successors, into the Green Goblin gave him increased (but not superhuman) intelligence and limited super strength. Later, Norman's strength increased to about the same level as Spider-Man's. Furthermore, the Goblin has increased reflexes, speed and protection against injury. Osborne is also able to heal quickly from normally fatal injuries.
The Joker is a fictional character, the main villain of a comic book series published by DC Comics. He is Batman's main foe, being directly responsible for numerous tragedies in Batman's life, including the paralysis of Barbara Gordon and the death of Jason Todd, the second Robin. He first appeared in Batman #1, created by Jerry Robinson, Bill Finger and Bob Kane. Throughout his comic book appearances, the Joker has been portrayed as the main criminal with a variety of characterizations. His original and currently dominant image is that of a highly intelligent sociopath with a warped, sadistic sense of humor, while other versions have emphasized his sense of humor, eccentricities, and antics. Similarly, this character has many stories of origin in its long history.
The Kingpin, real name Wilson Fisk is a fictional Marvel Comics villain. He was created by Stan Lee and John Romita Sr., and first appeared in The Amazing Spider-Man #50 (July 1967). Kingpin is modeled on Sydney Greenstreet's character in The Maltese Falcon. Kingpin is a criminal mastermind and the leader of the New York mafia and criminal underworld. Kingpin is most recognizable for his huge build, white costume and his perpetual cigar and diamond-encrusted walking stick. He does not have super powers, but because of his position as a criminal mastermind he is an enemy of many a superhero. Punisher, Spider-Man and Daredevil in particular often get into trouble with him, but also Captain America, Moon Knight, Dr. Strange, The Avengers and Ghost Rider have already fought him.
7. Lex Luthor
Lex Luthor, full name Alexander Joseph Luthor, is a fictional DC Comics supervillain, and Superman's nemesis. He was created by Jerry Siegel and Joe Shuster, and made his debut in Action Comics #23 (1940). Lex Luthor has played many different roles in the Superman stories. At first he was the stereotype of a mad scientist, then an embittered scientist who blamed Superman for the accident that left him bald, and now a corrupt and filthy rich businessman. Making his debut in Action Comics #23, Luthor was a deranged scientist headquartered in a floating city. His first misdeed was trying to start a war between two fictional European countries. This soon brought him into conflict with Superman.
Loki (also Looki, Loke, Lopt or Loptr) is the god of chaos and lies of Norse mythology. He is a troublemaker and a shapeshifter. He helps other gods, but often works against them as well. After he had a hand in the death of the god Balder, the other gods decided to imprison him. He was tied in a cave with his own son's entrails and a snake was hung over his head and the poison dripped on his face. Here he would stay until Ragnarok, the end of the world. In the ensuing war, he would battle against the other gods and Heimdall and himself would be the end of each other. Loki was one of the sons of Farbauti and Laufey and blood brother of Odin.
Magneto is a Marvel Comics character. He first appeared in X-Men #1 (September 1963), created by Stan Lee and Jack Kirby. Magneto is best known as a character from the X-Men comics, in which he was both an enemy and an ally of the X-Men team. He has been involved since the first X-Men comic. He also has several teams of mutants against them such as the Brotherhood of Mutants and the Acolytes. Magneto is one of the strongest mutants in the world, with the gift of controlling magnetism. He is one of the most complex characters in American comics. As a child, Magneto survived the Holocaust, and wants to save the mutant race from the same fate. Over the years, Magneto has gone from super villain to anti-hero and even superhero. His radical methods of helping the mutants often bring him into conflict with his old friend Charles Xavier. Magneto is the father of the superheroes Quicksilver, Scarlet Witch, and probably Polaris.
Venom is a character from Marvel Comics. Originally introduced as a supervillain and an enemy of the superhero Spider-Man, the character has since evolved into an anti-hero and sometimes even a full-fledged superhero. He first appeared in The Amazing Spider-Man #298 (March 1988). Venom is the result of a symbiosis between an alien life form and a human. The human who has been associated with this so-called “symbiote” the longest is Eddie Brock. Venom's powers depend heavily on the individuals the symbiote is connected to and has been bonded with. Because the symbiote was linked to Spider-Man for a long time, Venom has many of the same powers as Spider-Man including increased muscle strength, reflexes and the ability to crawl up walls. His strength ranges from "slightly stronger than Spider-Man" to "being able to lift a tank".
Apocalypse is one of the strongest mutants in the Marvel Universe, with a host of superhuman powers and abilities. He is often accompanied by four servants known as the Four Horsemen of Apocalypse. These are clearly based on the Horsemen of John's Revelation. Apocalypse is also one of the oldest mutants in the world, born sometime in the mid 30th century BC. After his powers developed, he appeared as a kind of "God of Death" in many ancient mythologies. However, he only really became active in the 20th and 21st centuries, when more and more mutants appeared. As a popular adversary to the X-Men, Apocalypse played a role in many storylines from the X-Men comics. In addition, he appeared in both X-Men animated series and in the video game X-Men Legends II: Rise of Apocalypse.
Brainiac is a fictional supervillain from the DC Comics Superman series. He was created by Otto Binder, and first appeared in Action Comics #242. Due to many stories about time travel and cloning, combined with DC's adaptation of continuity in its comics, many different versions of Brainiac exist. Brainiac played a number of pivotal roles in DC Comics stories in the years that followed. For example, he arranged an invasion against Earth in the story "Panic in the Sky", and after Superman's death and return (in the story "Death of Superman") tried to make everyone think that the returned Superman was an imposter. In The Doomsday Wars storyline, Brainiac merged himself with the creature Doomsday. This temporarily made him the strongest being in the universe. The merger didn't last long because Doomsday opposed it.
Bullseye is a fictional Marvel Comics supervillain, and a regular enemy of Daredevil. He was created by Marv Wolfman and John Romita Sr., and drawn for the first time in a strip by Bob Brown. Bullseye made his debut in Daredevil (1st series), #131 (March 1976). He also appeared in the movie Daredevil and some computer games. Bullseye has no superhuman powers. On the other hand, he has the unsurpassed ability to turn almost any object into a deadly projectile. That makes him even more dangerous than most characters who do have superpowers. Bullseye can do things with objects that are only possible in fiction, such as, open someone's throat with a playing card, spit his own tooth through someone's skull, throw a paper airplane to another roof meters away and kill someone with a toothpick through a window that yards away to throw. While in prison, Bullseye was diagnosed with a rare red/green color blindness called protanopia.
Darkseid is a fictional DC Comics supervillain. He is primarily an opponent of Superman. The character was created by Jack Kirby as part of the Fourth World comic book series. He made his debut in Superman's Pal Jimmy Olsen #134 (November 1970). Darkseid is very powerful because he is a gods. His primary power is the Omega Effect, a form of energy he can fire from his eyes. This energy is not only an attack, but can also teleport people and objects to other locations. Darkseid has precise control over his Omega Effect beams and can even fire them around a corner. The rays can penetrate almost any material. Darkseid further possesses superhuman strength and stamina that can rival even Superman's. Darkseid can heal very quickly if injured. Darkseid also possesses psionic powers. He can manipulate matter on a molecular level with his thoughts. He can use telekinesis and telepathy for various effects. Darkseid is very intelligent. He is known as a master strategist and planner, with access to Apokolips' entire technological resources.
Doomsday is a fictional DC Comics supervillain. He is a regular enemy of Superman. The character was created by Dan Jurgens, and made his debut in Superman: The Man of Steel #17 (Nov. 1992). Doomsday is best known and infamous as the creature that killed Superman in the 1993 storyline The Death of Superman. Doomsday was created through a process of cloning and accelerated evolution. During his creation, he was killed several times by the creatures of prehistoric Krypton, each time coming back to life with immunity to whatever killed him. Through this process of dying and then coming back to life stronger, Doomsday can continue to adapt. The time it takes him to come back to life varies. In the battle with Superman, in which Doomsday's body remained virtually undamaged, he regained consciousness after a few months. But once Imperiex had reduced him to a skeleton, it would have taken at least 100 years for Doomsday to recover without outside help.
Galactus, also known as Devourer of Worlds or Ravager of Planets, is a fictional creature from the Marvel Comics. Galactus is a so-called cosmic being. Created by Stan Lee and Jack Kirby, he first appeared in Fantastic Four #48. Galactus has threatened several times to devour Earth as well. The first time, however, he was driven off by the Fantastic Four, aided by the Watcher and Galactus' former servant Silver Surfer, by threatening him with Mr. Fantastic's weapon the Ultimate Nullifier. Although Galactus resolved not to attack Earth again after this failed attempt, he returned several times. Once he was weakened enough by the Fantastic Four, the Avengers and Dr. Strange to beat him.
Mystique (Raven Darkholme) is a character from Marvel Comics. She mainly appears in X-Men comics. Created by Chris Claremont and Jim Mooney, she first appeared in Ms. Marvel #17 (May 1978). Mystique is a mutant with the gift of shapeshifting. In her natural form, she has blue skin, red hair, and yellow eyes, but her strength allows her to assume almost any form. She is already over 84 years old, but thanks to her mutation she still looks young. She is the biological mother of Nightcrawler and Craydon Creed, and the foster mother of Rogue. For most of her life, Mystique was a supervillain. She led the Brotherhood of Mutants, among others, and served as an assassin.
18. Ra's al Ghul
Ra's al Ghul is a fictional DC Comics supervillain. He is primarily an enemy of Batman. He was created by Dennis O'Neil and Neal Adams. Ra's al Ghul was created as a sort of James Bond-esque villain to give Batman a more epic foe. Ra's al Ghul's history was told in Dennis O'Neil and Norm Breyfogle's graphic novel Batman: Birth of the Demon (1992). Ra's al Ghul was born 600 years ago to a nomadic tribe in a desert somewhere in Arabia. From an early age he had an interest in science. Since he could not learn this as a nomad, he left his tribe and moved to the city. He became a physician.
Sinestro (full name: Thaal Sinestro) is a DC Comics supervillain. He was created by John Broome and Gil Kane. Sinestro is the former mentor and nemesis of Hal Jordan, aka the superhero Green Lantern. Sinestro made his debut in Green Lantern (vol. 2) #7 (July-August 1961). Sinestro is a native of the planet Korugar, in space sector 1417. He was initially a member of the Green Lantern Corps, and was known as one of the best Green Lanterns. As time passed, Sinestro became more and more obsessed with not only protecting his sector, but also maintaining order in the community at all costs. He concluded that this was best achieved by conquering Korugar and ruling as a dictator. When Hal Jordan joined the Green Lantern Corps, Sinestro became his mentor. Jordan was horrified by his mentor's fascist methods, but Sinestro insisted that only an iron fist could truly protect a planet. When Jordan enlisted the help of other Green Lanterns, Sinestro's true nature was revealed, and he had to face the Guardians of the Universe.
Thanos is a character from Marvel Comics. Created by Jim Starlin, he made his debut in Iron Man #55 (February 1973). His name is derived from Thanatos, the personification of death in Greek Mythology. The character has also subsequently made appearances in animated series and video games based on the comics and the Marvel Cinematic Universe. He is ranked 46th on IGN's list of 100 Greatest Comic Book Super Villains of All Time. Thanos, like all Eternals, is superhumanly strong and has increased his strength through cybernetic amplifications and mystical rituals. In addition, he has enormous stamina and is virtually invulnerable. He can absorb and re-fire large amounts of cosmic energy, and he possesses telepathy and telekinesis. Thanos has great knowledge of virtually every technology in existence and is an expert in teleportation and cross-dimensional travel. In addition, he is a master strategist and manipulator.